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نوع الوثيقة |
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مقال في مجلة دورية |
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عنوان الوثيقة |
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Glucose, glutamine, and ketone-body metabolism in human enterocytes Glucose, glutamine, and ketone-body metabolism in human enterocytes |
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الموضوع |
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الكيمياء الحيوية |
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لغة الوثيقة |
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الانجليزية |
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المستخلص |
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Suspensions of metabolically viable human small-intestinal epithelial cells (enterocytes) were used to assess the metabolism of substrate(s) normally derived from the blood circulation to the intestinal mucosa (glucose, glutamine, and ketone bodies). Glutamine, glutamate, and glucose were the only substrates that caused major increases in oxygen consumption by isolated human enterocytes. In human enterocytes 72% of glucose could be accounted for as lactate. Human enterocytes utilized glutamine at about 14.90 mumol/min/g dry wt, with glutamate, alanine, aspartate, and ammonia as the major end-products. Human enterocytes utilized 3-hydroxybutyrate and acetoacetate at similar rates. Under the experimental condition employed, the respiratory fuels of human enterocytes include glutamine, glucose, and to a lesser extent, ketone bodies as indicated in the proportion of oxygen consumption attributed to these fuels and to the extent of utilization |
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ردمد |
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0026-0495 |
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اسم الدورية |
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Metabolism |
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المجلد |
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37 |
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العدد |
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6 |
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سنة النشر |
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1408 هـ
1988 م |
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نوع المقالة |
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مقالة علمية |
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تاريخ الاضافة على الموقع |
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Thursday, November 24, 2011 |
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الباحثون
| عبدالرحمن آشي | Ashy, AbdulRahman | باحث رئيسي | دكتوراه | |
| محمد العرضاوي | Ardawi, Mohammed | باحث مشارك | دكتوراه | |
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