تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Study of ochratoxin A as an nvironmental risk that causes renal injury in breast-fed Egyptian infants
Study of ochratoxin A as an nvironmental risk that causes renal injury in breast-fed Egyptian infants
 
لغة الوثيقة : الانجليزية 
المستخلص : Ochratoxin A (OTA) constitutes a real human threat. Its presence in human milk has previously been reported in different countries. This study is the first Egyptian report on the presence of OTA in both mothers’ milk and infants’ sera, addressing its correlation with infants’ kidney functions, which was not previously addressed in the literature. Fifty healthy breast-lactating mothers and their infants who were exclusively breast-fed for at least 4 months were included. All of them were subjected to a thorough laboratory evaluation including determination of OTA concentration by high-performance liquid chromatography. Thirty-six mothers (72%) and their infants had been contaminated with OTA. Univariate analysis showed that the presence of OTA was associated with significantly higher levels of urinary b2 microglobulin and microalbuminuria. Multivariate logistic regression analysis showed that there was a significant correlation between a higher OTA level in infants’ sera and the degree of microalbuminuria. Mothers and their infants in our locality are exposed to a high OTA contamination rate (72%). To establish the role of OTA in causation of future renal dysfunction for infants, large controlled studies are warranted. 
ردمد : 0931-041X 
اسم الدورية : Pediatr Nephrol 
المجلد : 1 
العدد : 21 
سنة النشر : 1426 هـ
2006 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Saturday, May 15, 2010 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
أسامة جابرGaber, Osama باحثدكتوراه 

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اسم الملفالنوعالوصف
 26664.doc doc 

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