Document Details Document Type : Article In Journal  Document Title : Hodgkin’s lymphoma with exuberant granulomatous reaction Hodgkin’s lymphoma with exuberant granulomatous reaction   Subject : Pathology  Document Language : English  Abstract : We report a 36-year-old woman, presented with cervical lymphadenopathy and low-grade fever. Two fine needle aspiration cytology and one excisional biopsy were performed in the referral hospital, all showed granulomatous lesions without necrosis. A tentative diagnosis of tuberculosis was made, and she started on antituberculous treatment. However, there was no clinical improvement. She presented to our institution one year after the initial diagnosis, and a new biopsy from the cervical lymph node revealed effacement of the whole node by marked non-necrotizing granulomatous reaction. However, there were scattered large cells with few classic Reed-Sternberg cells between the granulomas. Immunohistochemistry reveals strong reaction of CD15 and CD30, and negative staining for CD45RB, CD45RO, and CD20. These findings confirmed the diagnosis of Hodgkin's lymphoma with remarkable granulomatous reaction that almost masked the malignant component. She was treated with chemotherapy, and she showed an excellent response  ISSN : 0379-5284  Journal Name : The Saudi Medical Journal  Volume : 27  Issue Number : 12  Publishing Year : 1427 AH 2006 AD  Article Type : Case Report  Added Date : Monday, August 24, 2009  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email جودة المغربي Al-Maghrabi, Jaudah Investigator Doctorate   علي صوان Sawan, Ali Researcher Doctorate   Files File Name Type Description  20284.pdf pdf Hodgkin’s lymphoma with exuberant Back To Researches Page