Document Details

Document Type : Article In Journal 
Document Title :
Effect of Itraconazole and Terbinafine on Leishmania Major Promastigotes
Effect of Itraconazole and Terbinafine on Leishmania Major Promastigotes
 
Document Language : English 
Abstract : The antiporliferative effect induced in vitro by two antifungal compounds, the azole itraconazole and the allylamine terbinafine on Leishmania major promastigotes are reported. Treatment of promastigote cultures with itraconazole or with terbinafine induced growth arrest. Concentrations of 0.75 µ/I or more of itraconazole induced cell lysis after 72 hours. However, even relatively large concentrations of terbinafine (2.0 µ/I) did not induce cell lysis. The IC 50 for itraconazole and terbinafine were 0.31 µl/1 and 3.3 µ/I respectively 
ISSN : 1319-1004 
Journal Name : Medical Science Journal 
Volume : 10 
Issue Number : 1 
Publishing Year : 1422 AH
2002 AD 
Article Type : Article 
Added Date : Monday, August 31, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سمير زموZimmo, Sameer ResearcherDoctorate 
هيثم زكائيZakai, Haytham InvestigatorDoctorate 

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