Document Details
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Document Type |
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Article In Journal |
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Document Title |
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Pattern of sepsis and meningitis in a University Hospital Pattern of sepsis and meningitis in a University Hospital |
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Document Language |
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English |
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Abstract |
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Objectives: To define the clinical and cerebrospinal fluid
(CSF) criteria that establishes a diagnosis of sepsis and
meningitis immediately on admission
Methods: One thousand children, aged one day to 13
years, presenting with acute onset of vomiting, fever,
convulsion, and diarrhea to the Pediatrics Department,
King Abdul-Aziz University Hospital, Jeddah, Kingdom
of Saudi Arabia from January 1997 to December 2000
were evaluated. Cases were subjected to history, clinical
examination, and lumbar puncture (LP). On admission,
chemical, cytological, and bacteriological examinations of
blood and CSF were carried out. Patients were divided
into sepsis (n=94) and meningitis (n=26) groups.
Results: The most common age liable for LP was in the
neonatal period (35.8%). Septic cases were more than
meningitis (78.3% versus 21.7%). Neonates were the
most commonly affected age in sepsis and meningitis; and
the predominant symptom in all groups was vomiting.
In meningitis, hemoglobin was less (p<0.05) while,
blood white blood cell counts (WBCs) (p<0.05), blood
neutrophils (p<0.05), CSF-chloride (p<0.000) and CSFWBCs
(p<0.001) were more than sepsis. In meningitis, a
positive correlation was found between CSF-glucose with
WBCs (r=0.52, p<0.05), neutrophils (r=0.49, p<0.05),
and blood-glucose (r=0.56, p<0.01); and between CSFWBCs
and CSF-protein (r=0.55, p<0.01). In sepsis, a
positive correlation was found between CSF-lymphocyte
and CSF-red blood cell count (r=0.37, p<0.001).
Conclusion: More septic cases were admitted to the
Pediatric Department through Emergency than meningitis
cases. The most common pediatric patients liable to
LP were neonates, and the most common presenting
symptom was vomiting. Children with vomiting and
convulsion and no organism in CSF must be carefully
examined, and urine and blood culture must be collected.
These children must be closely observed in hospital and
re-evaluated by a pediatrician. |
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ISSN |
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1658-3183 |
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Journal Name |
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Neurosciences |
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Volume |
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13 |
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Issue Number |
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1 |
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Publishing Year |
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1429 AH
2008 AD |
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Article Type |
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Article |
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Added Date |
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Tuesday, April 1, 2008 |
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Researchers
| نادية فدا | Fida, Nadia | Researcher | Doctorate | |
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Files
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Pattern - 20070309.pdf
| pdf | مشاهدة المقالة العلمية كاملة |
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