Document Details
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Document Type |
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Article In Journal |
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Document Title |
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Electrolyte Disturbances in Patients With Chronic, Stable Asthma Electrolyte Disturbances in Patients With Chronic, Stable Asthma |
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Document Language |
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English |
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Abstract |
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Objective: To determine the prevalence of electrolyte disturbances in patients with chronic,
stable asthma, and to assess whether the therapeutic agents used to treat chronic asthma have an
effect on abnormal electrolyte levels.
Design: Prospective, hospital-based, cross-sectional study.
Setting: University teaching hospital in Jeddah, Saudi Arabia.
Patients: Patients with chronic, stable asthma.
Method: Ninety-three consecutive patients with chronic, stable asthma were involved in the study.
On the day of the visit to the asthma clinic, particulars such as age, sex, duration of asthma, and
details of drug therapy were obtained from each asthmatic patient. Serum potassium, magnesium,
phosphorus, calcium, and sodium levels were measured. Normal values were as follows:
potassium, 3.5 to 5 mmol/L; magnesium, 0.74 to 1.2 mmol/L; phosphorus, 0.8 to 1.4 mmol/L; and
calcium, 2.1 to 2.6 mmol/L.
Results: Electrolyte disturbances were found in 43% of the patients; 85% of the patients had one
electrolyte disturbance, 10% had two electrolyte disturbances, and 5% had three electrolyte
disturbances. The highest proportions were for magnesium (26.9%) and phosphorus (15.1%)
[serum levels were 0.69 6 0.04 mmol/L and 0.64 6 0.09 mmol/L, respectively], the lowest
proportions were for potassium (5.4%) and sodium (4.3%) [serum levels were 3.3 6 0.01 mmol/L
and 133 6 0.01 mmol/L, respectively], and no patient had a calcium disturbance. Logistic
regression analysis showed no statistically significant association between the therapy used and
electrolyte disturbances.
Conclusion: Hypomagnesemia and hypophosphatemia were found to be the two most common
electrolyte disturbances in patients with chronic, stable asthma. Therapeutic agents used to treat
patients with chronic asthma have no effect on abnormal electrolyte levels. The underlying cause
still remains unclear. |
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ISSN |
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0012-3692 |
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Journal Name |
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Chest |
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Volume |
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120 |
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Issue Number |
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2 |
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Publishing Year |
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1422 AH
2001 AD |
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Article Type |
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Article |
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Added Date |
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Friday, October 16, 2009 |
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Researchers
| عمر العمودي | Alamoudi, Omer | Researcher | Doctorate | |
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