Document Details

Document Type : Article In Journal 
Document Title :
EXTRA-ARTICULAR MANIFESTATIONS OF RHEUMATOID ARTHRITIS: A HOSPITAL BASED STUDY.
EXTRA-ARTICULAR MANIFESTATIONS OF RHEUMATOID ARTHRITIS: A HOSPITAL BASED STUDY.
 
Document Language : English 
Abstract : BACKGROUND AND OBJECTIVE: The frequency of extra-articular manifestations in rheumatoid arthritis (ExRA) differs from one country to another, so we investigated ExRA frequency in a well-defined hospital patient populattion with rheumatoid arthritis (RA) in Saudi Arabia. We also examined possible predictors of the development ExRA. METHODS: A retrospective analysis was conducted of all patients diagnosed with RA at a university hospital duriing a 4-year period. Cases were classified according to the 1987 American College of Rheumatology criteria for RA, and the frequency of ExRA was recorded. RESULTS: Of 140 patients who fulfilled the criteria for the diagnosis of RA, 98 (70%) developed ExRA features. Anemia occurred in 61%, thrombocytosis in 16%, pulmonary involvement in 10%, and renal amyloidosis, vascculitis and Felty syndrome were present in 6%, 2% and 1%, respectively. The mortality rate was high (16%) in pattients with ExRA. The predictors for mortality were lung involvement, age over 50 years and kidney amyloidosis. CONCLUSION: ExRA were present in a substantial proportion of our patients, which lead to a worse disease outcome. Anemia, thrombocytosis and respiratory system involvement were the commonest. Early recognition and treatment are important to decrease mortality. 
ISSN : 0930-2794 
Journal Name : Ann Saudi Med 
Volume : 29 
Issue Number : 3 
Publishing Year : 1430 AH
2009 AD 
Article Type : Article 
Added Date : Sunday, May 16, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
عائشة الغامديAlghamdi, Aisha ResearcherDoctorateAalghamdius2009@hotmail.com
سوزان عطارAttar, Suzan ResearcherDoctorate 

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