Document Details

Document Type : Article In Journal 
Document Title :
Effects of Honey on Stress-Induced Ulcers in Rats
Effects of Honey on Stress-Induced Ulcers in Rats
 
Document Language : English 
Abstract : The effects of honey on stress-induced ulcers were examined in rats. Stress was induced by using the Strain and Water Immersion technique (6 hours). Ulcer incidence and severity were quantified by an ulcer index.A honey solution, which consisted of 40% honey in water, was administered orally in dose-volumes of 1,3, 5.7 and 14 mt/kg, 20 mm before stress induction in 48 hr-fasting rats. Control rats receivedequivalent volumes of a Honey Control Solution (HCS). The systemic effects of honey on stress induced ulcers were examined by intraperitoneal injection of hcuxey (3.5 mt/kg) 10 mm. before stress induction. The effect of a honey solution on gastro-mntestinal tract motility was examined by using a charcoal meal incorporated with honey or tiCS. Results show that intraluminal honey administration lowers the incidence of stress-induced ulcers by 15% relative to that of control rats who received saline (X2 = 3.1, P = .07). Rats pretreated with a honey solution (3,5,7 and 14 mt/kg) showed a significantly lower ulcer index than HCS-pretreated rats (P < .05). Incorporation of honey into a charcoal meal lowers G.LT. stress-induced hypermotility by 37.8% of matched control received saline incorporated charcoal meal. It was concluded that intraluminal administration of honey decreases the severity of stress-induced ulcers in rats 
ISSN : 1319-1004 
Journal Name : Medical Science Journal 
Volume : 7 
Issue Number : 1 
Publishing Year : 1419 AH
1999 AD
 
Article Type : Article 
Added Date : Friday, April 20, 2012 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
عدنان المزروعAl-Mazrooa, Adnan InvestigatorDoctorate 
منصور سليمانSulaiman, Mansour ResearcherDoctorate 

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